Love your liver.
ShiftSetGo Liver Support Complex is a potent blend of botanicals, functional mushrooms, and NAC to help protect your liver from the harsh effects of oxidative stress.
The liver is tasked with over 500 metabolic and biochemical tasks that affect your overall health. This hard working organ plays a major role in metabolism, immunity, digestion, and detoxification. Keeping your liver health is key in optimizing health. Unfortunately, there's a lot that can interfere with liver function—excessive alcohol consumption, inflammation, the buildup of fats, scarring of liver tissue from illnesses, and overuse of medications such as acetaminophen.
The support your liver deserves.
The research-backed ingredients in our Liver Support Complex have been shown to help protect the liver while actively contributing to detoxification processes.
N-Acetyl-L-Cysteine (NAC) is a powerful antioxidant and ant-inflammatory that exerts an impressive positive effect against oxidative stress. In addition to its own antioxidant capabilities, it also increases glutathione—also called the master antioxidant. Glutathione has been shown to decrease oxidative stress, reduce cell damage in nonalcoholic fatty liver disease, and improve insulin resistance. Poor nutrition, environmental toxins, stress, and age can all reduce glutathione levels.
Reishi is a functional mushroom that has been shown to have a laundry list of beneficial effects on the liver. This includes increasing liver enzymes used in detoxification, inhibiting liver damage, protecting against post-injury dysfunction, increasing glutathione, and boosting immune cells that can help clear toxins and viruses.
Cordyceps is a fungi that has shown promising potential health benefits that include reducing fatigue, increasing antioxidants, and lowering inflammation. Cordyceps have also improved liver enzyme levels and liver function in a growing number of studies.
Milk Thistle is a flowering herb that is rich in silymarin, a compound with antioxidant, antiviral, and anti-inflammatory properties. Studies have found that it can help reduce inflammation in the liver and damage caused by free radicals.
Chinese Skullcap is an herb that has potentially therapeutic effects on the liver. This is due to the active component, baicalin. Research suggest this compound may help enhance lipid metabolism, protect against liver injury from drugs and environmental toxins, and suppress inflammation and oxidative stress in the liver.
Schisandra is a berry rich in polyphenols and flavonoids with significant antioxidant activities. It has shown particular promise in improving liver function and protecting against stress-induced nonalcoholic fatty liver.
Burdock root is another plant rich in powerful antioxidants. It is used to help detoxify the blood and reduce inflammation.
A healthy liver is a happy liver.
Give this hard-working organ the support and love it deserves with the ShiftSetGo Liver Support Complex.
Abenavoli, L., Capasso, R., Milic, N., & Capasso, F. (2010). Milk thistle in liver diseases: past, present, future. Phytotherapy research : PTR, 24(10), 1423–1432. https://doi.org/10.1002/ptr.3207
Chan, YS., Cheng, LN., Wu, JH. et al. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacol 19, 245–254 (2011). https://doi.org/10.1007/s10787-010-0062-4
de Andrade, K. Q., Moura, F. A., dos Santos, J. M., de Araújo, O. R., de Farias Santos, J. C., & Goulart, M. O. (2015). Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine. International journal of molecular sciences, 16(12), 30269–30308. https://doi.org/10.3390/ijms161226225
Federico, A., Dallio, M., & Loguercio, C. (2017). Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. Molecules (Basel, Switzerland), 22(2), 191. https://doi.org/10.3390/molecules22020191
Honda, Y., Kessoku, T., Sumida, Y., Kobayashi, T., Kato, T., Ogawa, Y., Tomeno, W., Imajo, K., Fujita, K., Yoneda, M., Kataoka, K., Taguri, M., Yamanaka, T., Seko, Y., Tanaka, S., Saito, S., Ono, M., Oeda, S., Eguchi, Y., Aoi, W., … Nakajima, A. (2017). Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study. BMC gastroenterology, 17(1), 96. https://doi.org/10.1186/s12876-017-0652-3
Jang, M. K., Nam, J. S., Kim, J. H., Yun, Y. R., Han, C. W., Kim, B. J., Jeong, H. S., Ha, K. T., & Jung, M. H. (2016). Schisandra chinensis extract ameliorates nonalcoholic fatty liver via inhibition of endoplasmic reticulum stress. Journal of ethnopharmacology, 185, 96–104. https://doi.org/10.1016/j.jep.2016.03.021
Park, S. Y., Jung, S. J., Ha, K. C., Sin, H. S., Jang, S. H., Chae, H. J., & Chae, S. W. (2015). Anti-inflammatory effects of Cordyceps mycelium (Paecilomyces hepiali, CBG-CS-2) in Raw264.7 murine macrophages. Oriental pharmacy and experimental medicine, 15(1), 7–12. https://doi.org/10.1007/s13596-014-0173-3
Polachi, N., Bai, G., Li, T., Chu, Y., Wang, X., Li, S., Gu, N., Wu, J., Li, W., Zhang, Y., Zhou, S., Sun, H., & Liu, C. (2016). Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer - A comprehensive review. European journal of medicinal chemistry, 123, 577–595. https://doi.org/10.1016/j.ejmech.2016.07.070
Pu, H. J., Cao, Y. F., He, R. R., Zhao, Z. L., Song, J. H., Jiang, B., Huang, T., Tang, S. H., Lu, J. M., & Kurihara, H. (2012). Correlation between Antistress and Hepatoprotective Effects of Schisandra Lignans Was Related with Its Antioxidative Actions in Liver Cells. Evidence-based complementary and alternative medicine : eCAM, 2012, 161062. https://doi.org/10.1155/2012/161062
Wu, X., Zeng, J., Hu, J., Liao, Q., Zhou, R., Zhang, P., & Chen, Z. (2013). Hepatoprotective effects of aqueous extract from Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher basidiomycetes) on α-amanitin-induced liver injury in mice. International journal of medicinal mushrooms, 15(4), 383–391. https://doi.org/10.1615/intjmedmushr.v15.i4.60
Vasiljevic, J. D., Zivkovic, L. P., Cabarkapa, A. M., Bajic, V. P., Djelic, N. J., & Spremo-Potparevic, B. M. (2016). Cordyceps sinensis: Genotoxic Potential in Human Peripheral Blood Cells and Antigenotoxic Properties Against Hydrogen Peroxide by Comet Assay. Alternative therapies in health and medicine, 22 Suppl 2, 24–31.
Yang, Jy., Li, M., Zhang, Cl. et al. Pharmacological properties of baicalin on liver diseases: a narrative review. Pharmacol. Rep 73, 1230–1239 (2021). https://doi.org/10.1007/s43440-021-00227-1